The meta-epigenomic structure of purified human stem cell populations is defined at cis-regulatory sequences

The mechanism and significance of epigenetic variability in the same cell type between healthy individuals are not clear. Here, we purify human CD34+ hematopoietic stem and progenitor cells (HSPCs) from different individuals and find that there is increased variability of DNA methylation at loci wit...

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Detalles Bibliográficos
Autores principales: Wijetunga, N. Ari, Delahaye, Fabien, Zhao, Yong Mei, Golden, Aaron, Mar, Jessica C., Einstein, Francine H., Greally, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300104/
https://www.ncbi.nlm.nih.gov/pubmed/25327398
http://dx.doi.org/10.1038/ncomms6195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300104/
https://www.ncbi.nlm.nih.gov/pubmed/25327398
http://dx.doi.org/10.1038/ncomms6195

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