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The meta-epigenomic structure of purified human stem cell populations is defined at cis-regulatory sequences
The mechanism and significance of epigenetic variability in the same cell type between healthy individuals are not clear. Here, we purify human CD34+ hematopoietic stem and progenitor cells (HSPCs) from different individuals and find that there is increased variability of DNA methylation at loci wit...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300104/ https://www.ncbi.nlm.nih.gov/pubmed/25327398 http://dx.doi.org/10.1038/ncomms6195 |