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Inhibition of matrix metalloproteinases attenuates brain damage in experimental meningococcal meningitis

BACKGROUND: Approximately 7% of survivors from meningococcal meningitis (MM) suffer from neurological sequelae due to brain damage in the course of meningitis. The present study focuses on the role of matrix metalloproteinases (MMPs) in a novel mouse model of MM-induced brain damage. METHODS: The mo...

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Detalles Bibliográficos
Autores principales: Ricci, Susanna, Grandgirard, Denis, Wenzel, Michael, Braccini, Tiziana, Salvatore, Paola, Oggioni, Marco R, Leib, Stephen L, Koedel, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300156/
https://www.ncbi.nlm.nih.gov/pubmed/25551808
http://dx.doi.org/10.1186/s12879-014-0726-6