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Analysis of Genetic Code Ambiguity Arising from Nematode-Specific Misacylated tRNAs

The faithful translation of the genetic code requires the highly accurate aminoacylation of transfer RNAs (tRNAs). However, it has been shown that nematode-specific V-arm-containing tRNAs (nev-tRNAs) are misacylated with leucine in vitro in a manner that transgresses the genetic code. nev-tRNA(Gly)...

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Detalles Bibliográficos
Autores principales: Hamashima, Kiyofumi, Mori, Masaru, Andachi, Yoshiki, Tomita, Masaru, Kohara, Yuji, Kanai, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300185/
https://www.ncbi.nlm.nih.gov/pubmed/25602944
http://dx.doi.org/10.1371/journal.pone.0116981