Human Cerberus Prevents Nodal-Receptor Binding, Inhibits Nodal Signaling, and Suppresses Nodal-Mediated Phenotypes

The Transforming Growth Factor-ß (TGFß) family ligand Nodal is an essential embryonic morphogen that is associated with progression of breast and other cancers. It has therefore been suggested that Nodal inhibitors could be used to treat breast cancers where Nodal plays a defined role. As secreted a...

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Detalles Bibliográficos
Autores principales: Aykul, Senem, Ni, Wendi, Mutatu, Washington, Martinez-Hackert, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300205/
https://www.ncbi.nlm.nih.gov/pubmed/25603319
http://dx.doi.org/10.1371/journal.pone.0114954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300205/
https://www.ncbi.nlm.nih.gov/pubmed/25603319
http://dx.doi.org/10.1371/journal.pone.0114954

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