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Zirconium Ions Up-Regulate the BMP/SMAD Signaling Pathway and Promote the Proliferation and Differentiation of Human Osteoblasts

Zirconium (Zr) is an element commonly used in dental and orthopedic implants either as zirconia (ZrO(2)) or in metal alloys. It can also be incorporated into calcium silicate-based ceramics. However, the effects of in vitro culture of human osteoblasts (HOBs) with soluble ionic forms of Zr have not...

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Detalles Bibliográficos
Autores principales: Chen, Yongjuan, Roohani-Esfahani, Seyed-Iman, Lu, ZuFu, Zreiqat, Hala, Dunstan, Colin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300214/
https://www.ncbi.nlm.nih.gov/pubmed/25602473
http://dx.doi.org/10.1371/journal.pone.0113426