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Candida albicans OPI1 Regulates Filamentous Growth and Virulence in Vaginal Infections, but Not Inositol Biosynthesis

ScOpi1p is a well-characterized transcriptional repressor and master regulator of inositol and phospholipid biosynthetic genes in the baker’s yeast Saccharomyces cerevisiae. An ortholog has been shown to perform a similar function in the pathogenic fungus Candida glabrata, but with the distinction t...

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Detalles Bibliográficos
Autores principales: Chen, Ying-Lien, de Bernardis, Flavia, Yu, Shang-Jie, Sandini, Silvia, Kauffman, Sarah, Tams, Robert N., Bethea, Emily, Reynolds, Todd B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300220/
https://www.ncbi.nlm.nih.gov/pubmed/25602740
http://dx.doi.org/10.1371/journal.pone.0116974