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Growth factor and ultrasound-assisted bioreactor synergism for human mesenchymal stem cell chondrogenesis

Ultrasound at 5.0 MHz was noted to be chondro-inductive, with improved SOX-9 gene and COL2A1 protein expression in constructs that allowed for cell-to-cell contact. To achieve tissue-engineered cartilage using macroporous scaffolds, it is hypothesized that a combination of ultrasound at 5.0 MHz and...

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Detalles Bibliográficos
Autores principales: Thakurta, Sanjukta Guha, Budhiraja, Gaurav, Subramanian, Anuradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300305/
https://www.ncbi.nlm.nih.gov/pubmed/25610590
http://dx.doi.org/10.1177/2041731414566529