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Cytotoxic Effects of Loperamide Hydrochloride on Canine Cancer Cells

Loperamide is a peripheral opiate agonist that can cause apoptosis and G2/M arrest in human cancer cell lines and may sensitize cells to chemotherapy. The objectives of this study were to investigate the effects of loperamide on viability, apoptosis and cell cycle kinetics in canine cancer cells and...

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Detalles Bibliográficos
Autores principales: REGAN, Rebecca Cohen, GOGAL, Robert Michael, BARBER, James Perry, TUCKFIELD, Richard Cary, HOWERTH, Elizabeth Wynne, LAWRENCE, Jessica Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300369/
https://www.ncbi.nlm.nih.gov/pubmed/25649936
http://dx.doi.org/10.1292/jvms.13-0537