Tumor necrosis factor-α-accelerated degradation of type I collagen in human skin is associated with elevated matrix metalloproteinase (MMP)-1 and MMP-3 ex vivo

Tumor necrosis factor (TNF)-α induces matrix metalloproteinases (MMPs) that may disrupt skin integrity. We have investigated the effects and mechanisms of exogenous TNF-α on collagen degradation by incubating human skin explants in defined serum-free media with or without TNF-α (10 ng/ml) in the abs...

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Detalles Bibliográficos
Autores principales: Ågren, Magnus S., Schnabel, Reinhild, Christensen, Lise H., Mirastschijski, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300401/
https://www.ncbi.nlm.nih.gov/pubmed/25457675
http://dx.doi.org/10.1016/j.ejcb.2014.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300401/
https://www.ncbi.nlm.nih.gov/pubmed/25457675
http://dx.doi.org/10.1016/j.ejcb.2014.10.001

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