Bisoprolol and Bisoprolol-Valsartan Compatibility Studied by Differential Scanning Calorimetry, Nuclear Magnetic Resonance and X-Ray Powder Diffractometry

PURPOSE: The objective of this study was to evaluate the thermal behavior of crystalline and amorphous bisoprolol fumarate and its compatibility with amorphous valsartan. This pharmacologically relevant drug combination is a potential candidate for fixed-dose combination formulation. METHODS: DSC an...

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Detalles Bibliográficos
Autores principales: Skotnicki, Marcin, Aguilar, Juan A., Pyda, Marek, Hodgkinson, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300422/
https://www.ncbi.nlm.nih.gov/pubmed/25115829
http://dx.doi.org/10.1007/s11095-014-1471-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300422/
https://www.ncbi.nlm.nih.gov/pubmed/25115829
http://dx.doi.org/10.1007/s11095-014-1471-7

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