Specific insulin/IGF1 hybrid receptor activation assay reveals IGF1 as a more potent ligand than insulin

This novel method enables specific measurement of the activation of hybrid receptors formed between the Insulin Receptor (IR) and the Insulin-like Growth Factor 1 Receptor (IGF1R). These hybrid receptors are present in tissues and cell lines expressing both IR and IGF1R. It is therefore challenging...

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Detalles Bibliográficos
Autor principal: Slaaby, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300458/
https://www.ncbi.nlm.nih.gov/pubmed/25604425
http://dx.doi.org/10.1038/srep07911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300458/
https://www.ncbi.nlm.nih.gov/pubmed/25604425
http://dx.doi.org/10.1038/srep07911

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