Cargando…

Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle

DNA replication, transcription and repair involve the recruitment of protein complexes that change their composition as they progress along the genome in a directed or strand-specific manner. Chromatin immunoprecipitation in conjunction with hidden Markov models (HMMs) has been instrumental in under...

Descripción completa

Detalles Bibliográficos
Autores principales: Zacher, Benedikt, Lidschreiber, Michael, Cramer, Patrick, Gagneur, Julien, Tresch, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300491/
https://www.ncbi.nlm.nih.gov/pubmed/25527639
http://dx.doi.org/10.15252/msb.20145654