Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation

Ribosome profiling data report on the distribution of translating ribosomes, at steady-state, with codon-level resolution. We present a robust method to extract codon translation rates and protein synthesis rates from these data, and identify causal features associated with elongation and translatio...

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Detalles Bibliográficos
Autores principales: Pop, Cristina, Rouskin, Silvi, Ingolia, Nicholas T, Han, Lu, Phizicky, Eric M, Weissman, Jonathan S, Koller, Daphne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300493/
https://www.ncbi.nlm.nih.gov/pubmed/25538139
http://dx.doi.org/10.15252/msb.20145524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300493/
https://www.ncbi.nlm.nih.gov/pubmed/25538139
http://dx.doi.org/10.15252/msb.20145524

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