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DEK is a potential marker for aggressive phenotype and irinotecan-based therapy response in metastatic colorectal cancer

BACKGROUND: DEK is a transcription factor involved in stabilization of heterochromatin and cruciform structures. It plays an important role in development and progression of different types of cancer. This study aims to analyze the role of DEK in metastatic colorectal cancer. METHODS: Baseline DEK e...

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Detalles Bibliográficos
Autores principales: Martinez-Useros, Javier, Rodriguez-Remirez, Maria, Borrero-Palacios, Aurea, Moreno, Irene, Cebrian, Arancha, Gomez del Pulgar, Teresa, del Puerto-Nevado, Laura, Vega-Bravo, Ricardo, Puime-Otin, Alberto, Perez, Nuria, Zazo, Sandra, Senin, Clara, Fernandez-Aceñero, Maria J, Soengas, Maria S, Rojo, Federico, Garcia-Foncillas, Jesus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300837/
https://www.ncbi.nlm.nih.gov/pubmed/25515240
http://dx.doi.org/10.1186/1471-2407-14-965