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Monocyte trafficking to the brain with stress and inflammation: a novel axis of immune-to-brain communication that influences mood and behavior

HIGHLIGHTS: Psychological stress activates neuroendocrine pathways that alter immune responses. Stress-induced alterations in microglia phenotype and monocyte priming leads to aberrant peripheral and central inflammation. Elevated pro-inflammatory cytokine levels caused by microglia activation and r...

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Detalles Bibliográficos
Autores principales: Wohleb, Eric S., McKim, Daniel B., Sheridan, John F., Godbout, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300916/
https://www.ncbi.nlm.nih.gov/pubmed/25653581
http://dx.doi.org/10.3389/fnins.2014.00447