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Monocyte trafficking to the brain with stress and inflammation: a novel axis of immune-to-brain communication that influences mood and behavior
HIGHLIGHTS: Psychological stress activates neuroendocrine pathways that alter immune responses. Stress-induced alterations in microglia phenotype and monocyte priming leads to aberrant peripheral and central inflammation. Elevated pro-inflammatory cytokine levels caused by microglia activation and r...
Autores principales: | Wohleb, Eric S., McKim, Daniel B., Sheridan, John F., Godbout, Jonathan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300916/ https://www.ncbi.nlm.nih.gov/pubmed/25653581 http://dx.doi.org/10.3389/fnins.2014.00447 |
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