Cargando…

Development of Substrate-Selective Probes for Affinity Pulldown of Histone Demethylases

[Image: see text] JmjC-domain containing histone demethylases (JHDMs) play critical roles in many key cellular processes and have been implicated in multiple disease conditions. Each enzyme within this family is known to have a strict substrate scope, specifically the position of the lysine within t...

Descripción completa

Detalles Bibliográficos
Autores principales: Marholz, Laura J., Chang, Le, Old, William M., Wang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301071/
https://www.ncbi.nlm.nih.gov/pubmed/25335116
http://dx.doi.org/10.1021/cb5006867