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Development of Substrate-Selective Probes for Affinity Pulldown of Histone Demethylases
[Image: see text] JmjC-domain containing histone demethylases (JHDMs) play critical roles in many key cellular processes and have been implicated in multiple disease conditions. Each enzyme within this family is known to have a strict substrate scope, specifically the position of the lysine within t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301071/ https://www.ncbi.nlm.nih.gov/pubmed/25335116 http://dx.doi.org/10.1021/cb5006867 |