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Inactivation of Multiple Bacterial Histidine Kinases by Targeting the ATP-Binding Domain
[Image: see text] Antibacterial agents that exploit new targets will be required to combat the perpetual rise of bacterial resistance to current antibiotics. We are exploring the inhibition of histidine kinases, constituents of two-component systems. Two-component systems are the primary signaling p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301073/ https://www.ncbi.nlm.nih.gov/pubmed/25531939 http://dx.doi.org/10.1021/cb5008019 |