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Protein Prenylation: Enzymes, Therapeutics, and Biotechnology Applications

[Image: see text] Protein prenylation is a ubiquitous covalent post-translational modification found in all eukaryotic cells, comprising attachment of either a farnesyl or a geranylgeranyl isoprenoid. It is essential for the proper cellular activity of numerous proteins, including Ras family GTPases...

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Detalles Bibliográficos
Autores principales: Palsuledesai, Charuta C., Distefano, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301080/
https://www.ncbi.nlm.nih.gov/pubmed/25402849
http://dx.doi.org/10.1021/cb500791f