Cargando…

Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors

[Image: see text] Autophagy is a conserved cellular process that involves the degradation of cellular components for energy maintenance and cytoplasmic quality control that has recently gained interest as a novel target for a variety of human diseases, including cancer. A prime candidate to determin...

Descripción completa

Detalles Bibliográficos
Autores principales: Lazarus, Michael B., Novotny, Chris J., Shokat, Kevan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301081/
https://www.ncbi.nlm.nih.gov/pubmed/25551253
http://dx.doi.org/10.1021/cb500835z