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Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors
[Image: see text] Autophagy is a conserved cellular process that involves the degradation of cellular components for energy maintenance and cytoplasmic quality control that has recently gained interest as a novel target for a variety of human diseases, including cancer. A prime candidate to determin...
Autores principales: | Lazarus, Michael B., Novotny, Chris J., Shokat, Kevan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301081/ https://www.ncbi.nlm.nih.gov/pubmed/25551253 http://dx.doi.org/10.1021/cb500835z |
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