Spirodi(iminohydantoin) Products from Oxidation of 2′-Deoxyguanosine in the Presence of NH(4)Cl in Nucleoside and Oligodeoxynucleotide Contexts

[Image: see text] Upon oxidation of the heterocyclic ring in 2′-deoxyguanosine (dG), the initial electrophilic intermediate displays a wide range of reactivities with nucleophiles leading to many downstream products. In the present study, the product profiles were mapped when aqueous solutions of dG...

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Detalles Bibliográficos
Autores principales: Fleming, Aaron M., Armentrout, Erin I., Zhu, Judy, Muller, James G., Burrows, Cynthia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301082/
https://www.ncbi.nlm.nih.gov/pubmed/25539403
http://dx.doi.org/10.1021/jo502665p

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301082/
https://www.ncbi.nlm.nih.gov/pubmed/25539403
http://dx.doi.org/10.1021/jo502665p

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