Cargando…

Small Molecule Substrate Phosphorylation Site Inhibitors of Protein Kinases: Approaches and Challenges

[Image: see text] Protein kinases are important mediators of cellular communication and attractive drug targets for many diseases. Although success has been achieved with developing ATP-competitive kinase inhibitors, the disadvantages of ATP-competitive inhibitors have led to increased interest in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Breen, Meghan E., Soellner, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301090/
https://www.ncbi.nlm.nih.gov/pubmed/25494294
http://dx.doi.org/10.1021/cb5008376