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Contact-Induced Mitochondrial Polarization Supports HIV-1 Virological Synapse Formation

Rapid HIV-1 spread between CD4 T lymphocytes occurs at retrovirus-induced immune cell contacts called virological synapses (VS). VS are associated with striking T cell polarization and localized virus budding at the site of contact that facilitates cell-cell spread. In addition to this, spatial clus...

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Detalles Bibliográficos
Autores principales: Groppelli, Elisabetta, Starling, Shimona, Jolly, Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301097/
https://www.ncbi.nlm.nih.gov/pubmed/25320323
http://dx.doi.org/10.1128/JVI.02425-14