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Molecular Basis for Small Molecule Inhibition of G Protein-Coupled Receptor Kinases

[Image: see text] Small molecules that inhibit the protein kinase A, G, and C (AGC) family of serine/threonine kinases can exert profound effects on cell homeostasis and thereby regulate fundamental processes such as heart rate, blood pressure, and metabolism, but there is not yet a clinically appro...

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Detalles Bibliográficos
Autores principales: Homan, Kristoff T., Tesmer, John J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301174/
https://www.ncbi.nlm.nih.gov/pubmed/24984143
http://dx.doi.org/10.1021/cb5003976