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Degron Protease Blockade Sensor to Image Epigenetic Histone Protein Methylation in Cells and Living Animals
[Image: see text] Lysine methylation of histone H3 and H4 has been identified as a promising therapeutic target in treating various cellular diseases. The availability of an in vivo assay that enables rapid screening and preclinical evaluation of drugs that potentially target this cellular process w...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301175/ https://www.ncbi.nlm.nih.gov/pubmed/25489787 http://dx.doi.org/10.1021/cb5008037 |