Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells

BACKGROUND: Our prior characterization of RasGrf1 deficient mice uncovered significant defects in pancreatic islet count and size as well as beta cell development and signaling function, raising question about the mechanisms linking RasGrf1 to the generation of those “pancreatic” phenotypes. RESULTS...

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Detalles Bibliográficos
Autores principales: Manyes, Lara, Arribas, Monica, Gomez, Carmela, Calzada, Nuria, Fernandez-Medarde, Alberto, Santos, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301450/
https://www.ncbi.nlm.nih.gov/pubmed/25421944
http://dx.doi.org/10.1186/1471-2164-15-1019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301450/
https://www.ncbi.nlm.nih.gov/pubmed/25421944
http://dx.doi.org/10.1186/1471-2164-15-1019

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