Cargando…
Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells
BACKGROUND: Our prior characterization of RasGrf1 deficient mice uncovered significant defects in pancreatic islet count and size as well as beta cell development and signaling function, raising question about the mechanisms linking RasGrf1 to the generation of those “pancreatic” phenotypes. RESULTS...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301450/ https://www.ncbi.nlm.nih.gov/pubmed/25421944 http://dx.doi.org/10.1186/1471-2164-15-1019 |