Pleurotus ostreatus opposes mitochondrial dysfunction and oxidative stress in acetaminophen-induced hepato-renal injury

BACKGROUND: Acetaminophen (APAP)-induced toxicity is a predominant cause of acute hepatic and renal failure. In both humans and rodents toxicity begins with a reactive metabolite that binds to proteins. This leads to mitochondrial dysfunction and nuclear DNA fragmentation resulting in necrotic cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Naguib, Yahya M, Azmy, Rania M, Samaka, Rehab M, Salem, Mohamed F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301462/
https://www.ncbi.nlm.nih.gov/pubmed/25510860
http://dx.doi.org/10.1186/1472-6882-14-494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301462/
https://www.ncbi.nlm.nih.gov/pubmed/25510860
http://dx.doi.org/10.1186/1472-6882-14-494

Ejemplares similares