Cargando…

Activation of the intrinsic apoptosis pathway contributes to the induction of apoptosis in hepatocellular carcinoma cells by valproic acid

The level of histone deacetylation is closely associated with the genesis and development of tumors, but the antitumor effect and mechanism of the class I histone deacetylase inhibitor (HDACI) valproate acid sodium (VPA) on hepatocellular carcinoma cells has not been clearly demonstrated. In the pre...

Descripción completa

Detalles Bibliográficos
Autores principales: YANG, WEIHUA, ZHAO, XIA, PEI, FENGYAN, JI, MINGYU, MA, WANSHAN, WANG, YUNSHAN, JIANG, GUOSHENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301473/
https://www.ncbi.nlm.nih.gov/pubmed/25621063
http://dx.doi.org/10.3892/ol.2014.2739