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3-Bromopyruvate inhibits human gastric cancer tumor growth in nude mice via the inhibition of glycolysis

Tumor cells primarily depend upon glycolysis in order to gain energy. Therefore, the inhibition of glycolysis may inhibit tumor growth. Our previous study demonstrated that 3-bromopyruvate (3-BrPA) inhibited gastric cancer cell proliferation in vitro. However, the ability of 3-BrPA to suppress tumor...

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Detalles Bibliográficos
Autores principales: XIAN, SHU-LIN, CAO, WEI, ZHANG, XIAO-DONG, LU, YUN-FEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301496/
https://www.ncbi.nlm.nih.gov/pubmed/25621044
http://dx.doi.org/10.3892/ol.2014.2779