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Tamoxifen enhances the anticancer effect of cantharidin and norcantharidin in pancreatic cancer cell lines through inhibition of the protein kinase C signaling pathway

Cantharidin is an active constituent of mylabris, a traditional Chinese therapeutic agent. Cantharidin is a potent and selective inhibitor of protein phosphatase 2A (PP2A). Cantharidin has been previously reported to efficiently repress the growth of pancreatic cancer cells. However, excessively act...

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Detalles Bibliográficos
Autores principales: XIE, XIN, WU, MENG-YAO, SHOU, LIU-MEI, CHEN, LONG-PEI, GONG, FEI-RAN, CHEN, KAI, LI, DAO-MING, DUAN, WEI-MING, XIE, YU-FENG, MAO, YI-XIANG, LI, WEI, TAO, MIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301527/
https://www.ncbi.nlm.nih.gov/pubmed/25624908
http://dx.doi.org/10.3892/ol.2014.2711