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Attenuation of lysyl oxidase and collagen gene expression in keratoconus patient corneal epithelium corresponds to disease severity

PURPOSE: Keratoconus (KC) is characterized by progressive vision loss due to corneal thinning and structural abnormalities. It is hypothesized that KC is caused by deregulated collagen levels and collagen fibril-maturating enzyme lysyl oxidase (LOX). Further, it is currently not understood whether t...

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Detalles Bibliográficos
Autores principales: Shetty, Rohit, Sathyanarayanamoorthy, Arunapriya, Ramachandra, Reshma Airody, Arora, Vishal, Ghosh, Anuprita, Srivatsa, Purnima Raman, Pahuja, Natasha, Nuijts, Rudy M. M. A., Sinha-Roy, Abhijit, Mohan, Rajiv R., Ghosh, Arkasubhra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301596/
https://www.ncbi.nlm.nih.gov/pubmed/25593510