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DNMT3B7 Expression Promotes Tumor Progression to a More Aggressive Phenotype in Breast Cancer Cells

Epigenetic changes, such as DNA methylation, have been shown to promote breast cancer progression. However, the mechanism by which cancer cells acquire and maintain abnormal DNA methylation is not well understood. We have previously identified an aberrant splice form of a DNA methyltransferase, DNMT...

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Detalles Bibliográficos
Autores principales: Brambert, Patrick R., Kelpsch, Daniel J., Hameed, Rabia, Desai, Charmi V., Calafiore, Gianfranco, Godley, Lucy A., Raimondi, Stacey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301645/
https://www.ncbi.nlm.nih.gov/pubmed/25607950
http://dx.doi.org/10.1371/journal.pone.0117310