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Dense Collagen-I Matrices Enhance Pro-Tumorigenic Estrogen-Prolactin Crosstalk in MCF-7 and T47D Breast Cancer Cells

Breast cancers that express estrogen receptor alpha (ERα+) constitute the majority of breast tumors. Estrogen is a major driver of their growth, and targeting ER-mediated signals is a largely successful primary therapeutic strategy. Nonetheless, ERα+ tumors also result in the most breast cancer mort...

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Detalles Bibliográficos
Autores principales: Barcus, Craig E., Holt, Elizabeth C., Keely, Patricia J., Eliceiri, Kevin W., Schuler, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301649/
https://www.ncbi.nlm.nih.gov/pubmed/25607819
http://dx.doi.org/10.1371/journal.pone.0116891