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Fascin1-Dependent Filopodia are Required for Directional Migration of a Subset of Neural Crest Cells

Directional migration of neural crest (NC) cells is essential for patterning the vertebrate embryo, including the craniofacial skeleton. Extensive filopodial protrusions in NC cells are thought to sense chemo-attractive/repulsive signals that provide directionality. To test this hypothesis, we gener...

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Detalles Bibliográficos
Autores principales: Boer, Elena F., Howell, Elizabeth D., Schilling, Thomas F., Jette, Cicely A., Stewart, Rodney A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301650/
https://www.ncbi.nlm.nih.gov/pubmed/25607881
http://dx.doi.org/10.1371/journal.pgen.1004946