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Genetic diversity is a predictor of mortality in humans

BACKGROUND: It has been well-established, both by population genetics theory and direct observation in many organisms, that increased genetic diversity provides a survival advantage. However, given the limitations of both sample size and genome-wide metrics, this hypothesis has not been comprehensiv...

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Detalles Bibliográficos
Autores principales: Bihlmeyer, Nathan A, Brody, Jennifer A, Smith, Albert Vernon, Lunetta, Kathryn L, Nalls, Mike, Smith, Jennifer A, Tanaka, Toshiko, Davies, Gail, Yu, Lei, Mirza, Saira Saeed, Teumer, Alexander, Coresh, Josef, Pankow, James S, Franceschini, Nora, Scaria, Anish, Oshima, Junko, Psaty, Bruce M, Gudnason, Vilmundur, Eiriksdottir, Gudny, Harris, Tamara B, Li, Hanyue, Karasik, David, Kiel, Douglas P, Garcia, Melissa, Liu, Yongmei, Faul, Jessica D, Kardia, Sharon LR, Zhao, Wei, Ferrucci, Luigi, Allerhand, Michael, Liewald, David C, Redmond, Paul, Starr, John M, De Jager, Philip L, Evans, Denis A, Direk, Nese, Ikram, Mohammed Arfan, Uitterlinden, André, Homuth, Georg, Lorbeer, Roberto, Grabe, Hans J, Launer, Lenore, Murabito, Joanne M, Singleton, Andrew B, Weir, David R, Bandinelli, Stefania, Deary, Ian J, Bennett, David A, Tiemeier, Henning, Kocher, Thomas, Lumley, Thomas, Arking, Dan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301661/
https://www.ncbi.nlm.nih.gov/pubmed/25543667
http://dx.doi.org/10.1186/s12863-014-0159-7