Natalizumab restores aberrant miRNA expression profile in multiple sclerosis and reveals a critical role for miR-20b

OBJECTIVE: To identify microRNAs (miRNAs) regulated by anti-α4 integrin monoclonal antibody therapy (natalizumab) in the peripheral blood of patients with relapsing-remitting (RR) multiple sclerosis (MS) and to confirm their role in experimental settings in vivo. METHODS: In a longitudinal study of...

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Detalles Bibliográficos
Autores principales: Ingwersen, Jens, Menge, Til, Wingerath, Britta, Kaya, Derya, Graf, Jonas, Prozorovski, Tim, Keller, Andreas, Backes, Christina, Beier, Markus, Scheffler, Matthias, Dehmel, Thomas, Kieseier, Bernd C, Hartung, Hans-Peter, Küry, Patrick, Aktas, Orhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301674/
https://www.ncbi.nlm.nih.gov/pubmed/25642434
http://dx.doi.org/10.1002/acn3.152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301674/
https://www.ncbi.nlm.nih.gov/pubmed/25642434
http://dx.doi.org/10.1002/acn3.152

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