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Skeletal Muscle Fibrosis in the mdx/utrn+/- Mouse Validates Its Suitability as a Murine Model of Duchenne Muscular Dystrophy

Various therapeutic approaches have been studied for the treatment of Duchenne muscular dystrophy (DMD), but none of these approaches have led to significant long-term effects in patients. One reason for this observed inefficacy may be the use of inappropriate animal models for the testing of therap...

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Detalles Bibliográficos
Autores principales: Gutpell, Kelly M., Hrinivich, William T., Hoffman, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301874/
https://www.ncbi.nlm.nih.gov/pubmed/25607927
http://dx.doi.org/10.1371/journal.pone.0117306