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Pooled PCR testing strategy and prevalence estimation of submicroscopic infections using Bayesian latent class models in pregnant women receiving intermittent preventive treatment at Machinga District Hospital, Malawi, 2010

BACKGROUND: Low malaria parasite densities in pregnancy are a diagnostic challenge. PCR provides high sensitivity and specificity in detecting low density of parasites, but cost and technical requirements limit its application in resources-limited settings. Pooling samples for PCR detection was expl...

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Detalles Bibliográficos
Autores principales: Zhou, Zhiyong, Mitchell, Rebecca Mans, Gutman, Julie, Wiegand, Ryan E, Mwandama, Dyson A, Mathanga, Don P, Skarbinski, Jacek, Shi, Ya Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301903/
https://www.ncbi.nlm.nih.gov/pubmed/25522751
http://dx.doi.org/10.1186/1475-2875-13-509