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Pooled PCR testing strategy and prevalence estimation of submicroscopic infections using Bayesian latent class models in pregnant women receiving intermittent preventive treatment at Machinga District Hospital, Malawi, 2010
BACKGROUND: Low malaria parasite densities in pregnancy are a diagnostic challenge. PCR provides high sensitivity and specificity in detecting low density of parasites, but cost and technical requirements limit its application in resources-limited settings. Pooling samples for PCR detection was expl...
Autores principales: | Zhou, Zhiyong, Mitchell, Rebecca Mans, Gutman, Julie, Wiegand, Ryan E, Mwandama, Dyson A, Mathanga, Don P, Skarbinski, Jacek, Shi, Ya Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301903/ https://www.ncbi.nlm.nih.gov/pubmed/25522751 http://dx.doi.org/10.1186/1475-2875-13-509 |
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