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Association between HIF-1α C1772T/G1790A polymorphisms and cancer susceptibility: an updated systematic review and meta-analysis based on 40 case-control studies

BACKGROUND: HIF-1 (hypoxia-inducible factor 1) is a transcriptional activator that functions as a critical regulator of oxygen homeostasis. Recently, a large number of epidemiological studies have investigated the relationship between HIF-1α C1772T/G1790A polymorphisms and cancer susceptibility. How...

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Detalles Bibliográficos
Autores principales: Yan, Qing, Chen, Pin, Wang, Songtao, Liu, Ning, Zhao, Peng, Gu, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301938/
https://www.ncbi.nlm.nih.gov/pubmed/25496056
http://dx.doi.org/10.1186/1471-2407-14-950