Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

In comparative high-throughput sequencing assays, a fundamental task is the analysis of count data, such as read counts per gene in RNA-seq, for evidence of systematic changes across experimental conditions. Small replicate numbers, discreteness, large dynamic range and the presence of outliers requ...

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Detalles Bibliográficos
Autores principales: Love, Michael I, Huber, Wolfgang, Anders, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302049/
https://www.ncbi.nlm.nih.gov/pubmed/25516281
http://dx.doi.org/10.1186/s13059-014-0550-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302049/
https://www.ncbi.nlm.nih.gov/pubmed/25516281
http://dx.doi.org/10.1186/s13059-014-0550-8

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