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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

In comparative high-throughput sequencing assays, a fundamental task is the analysis of count data, such as read counts per gene in RNA-seq, for evidence of systematic changes across experimental conditions. Small replicate numbers, discreteness, large dynamic range and the presence of outliers requ...

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Detalles Bibliográficos
Autores principales:	Love, Michael I, Huber, Wolfgang, Anders, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302049/ https://www.ncbi.nlm.nih.gov/pubmed/25516281 http://dx.doi.org/10.1186/s13059-014-0550-8

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