Phosphorylation of Dok1 by Abl family kinases inhibits CrkI transforming activity

The Crk SH2/SH3 adaptor and the Abl nonreceptor tyrosine kinase were first identified as oncoproteins, and both can induce tumorigenesis when overexpressed or mutationally activated. We previously reported the surprising finding that inhibition or knockdown of Abl family kinases enhanced transformat...

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Detalles Bibliográficos
Autores principales: Ng, Khong Y., Yin, Taofei, Machida, Kazuya, Wu, Yi I., Mayer, Bruce J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302068/
https://www.ncbi.nlm.nih.gov/pubmed/25043303
http://dx.doi.org/10.1038/onc.2014.210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302068/
https://www.ncbi.nlm.nih.gov/pubmed/25043303
http://dx.doi.org/10.1038/onc.2014.210

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