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Oncogenic Role of Merlin/NF2 in Glioblastoma

Glioblastoma is the most common and aggressive primary brain tumor in adults, with a poor prognosis because of its resistance to radiotherapy and chemotherapy. Merlin/NF2 (neurofibromatosis type 2) is a tumor suppressor found to be mutated in most nervous system tumors; however, it is not mutated in...

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Detalles Bibliográficos
Autores principales: Guerrero, Paola A., Yin, Wei, Camacho, Laura, Marchetti, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302072/
https://www.ncbi.nlm.nih.gov/pubmed/25043298
http://dx.doi.org/10.1038/onc.2014.185