Mammalian transcriptional hotspots are enriched for tissue specific enhancers near cell type specific highly expressed genes and are predicted to act as transcriptional activator hubs

BACKGROUND: Transcriptional hotspots are defined as genomic regions bound by multiple factors. They have been identified recently as cell type specific enhancers regulating developmentally essential genes in many species such as worm, fly and humans. The in-depth analysis of hotspots across multiple...

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Detalles Bibliográficos
Autor principal: Joshi, Anagha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302108/
https://www.ncbi.nlm.nih.gov/pubmed/25547756
http://dx.doi.org/10.1186/s12859-014-0412-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302108/
https://www.ncbi.nlm.nih.gov/pubmed/25547756
http://dx.doi.org/10.1186/s12859-014-0412-0

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