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Edge effects in calling variants from targeted amplicon sequencing

BACKGROUND: Analysis of targeted amplicon sequencing data presents some unique challenges in comparison to the analysis of random fragment sequencing data. Whereas reads from randomly fragmented DNA have arbitrary start positions, the reads from amplicon sequencing have fixed start positions that co...

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Detalles Bibliográficos
Autores principales: Vijaya Satya, Ravi, DiCarlo, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302139/
https://www.ncbi.nlm.nih.gov/pubmed/25480444
http://dx.doi.org/10.1186/1471-2164-15-1073