Pharmacokinetics and pharmacodynamics of nab-paclitaxel in patients with solid tumors: Disposition kinetics and pharmacology distinct from solvent-based paclitaxel

The aim of this study was to characterize population pharmacokinetics and the exposure–neutropenia relationship with nanoparticle albumin-bound (nab)-paclitaxel in patients with solid tumors. Plasma and blood concentrations of paclitaxel and neutrophil data were collected from 150 patients with vari...

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Detalles Bibliográficos
Autores principales: Chen, Nianhang, Li, Yan, Ye, Ying, Palmisano, Maria, Chopra, Rajesh, Zhou, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Pharmacometrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302229/
https://www.ncbi.nlm.nih.gov/pubmed/24719309
http://dx.doi.org/10.1002/jcph.304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302229/
https://www.ncbi.nlm.nih.gov/pubmed/24719309
http://dx.doi.org/10.1002/jcph.304

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